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  1. The pseudo germ-free (PGF) model has been widely used to research the role of intestinal microbiota in drug metabolism and efficacy, while the modelling methods and the utilization of the PGF model are still n...

    Authors: Shanshan Wang, Qiuyu Wen, Yan Qin, Quan Xia, Chenlin Shen and Shuai Song
    Citation: Gut Pathogens 2023 15:15
  2. Bismuth salt is bacteriostatic and bactericidal against Helicobacter pylori (H. pylori). Little is known about the benefit of bismuth itself. Recently in Korea, government regulation changed to allow bismuth add-...

    Authors: Da Wit Shin, Dae Young Cheung, Ji Hee Song, Kyungseok Choi, Jihye Lim, Han Hee Lee, Jin Il Kim and Soo-Heon Park
    Citation: Gut Pathogens 2023 15:13
  3. Vancomycin-resistant enterococci (VRE) are well known agents that colonize the gastrointestinal tract of immunocompromised patients, especially those with hematologic malignancies. The aim of the current study...

    Authors: Preslava Mihaylova Hristova, Vladislav Milkov Nankov, Ivaylo Georgiev Hristov, Stefan Venelinov Trifonov, Alexandra Sashova Alexandrova and Hristina Yotova Hitkova
    Citation: Gut Pathogens 2023 15:12
  4. Interferon and nucleos(t)ide analogues are current therapeutic treatments for chronic Hepatitis B virus (HBV) infection with the limitations of a functional cure. Chrysin (5, 7-dihydroxyflavone) is a natural f...

    Authors: Sajad Ahmad Bhat, Syed Kazim Hasan, Zahoor Ahmad Parray, Zaheenul Islam Siddiqui, Shabnam Ansari, Ayesha Anwer, Saniya Khan, Fatima Amir, Mahboubeh Mehmankhah, Asimul Islam, Zarrin Minuchehr and Syed Naqui Kazim
    Citation: Gut Pathogens 2023 15:11
  5. Microorganisms have been linked to a variety of critical human disease, thanks to advances in sequencing technology and microbiology. The growing recognition of human microbe–disease relationships provides cru...

    Authors: Hassan Shokri Garjan, Yadollah Omidi, Mehdi Poursheikhali Asghari and Reza Ferdousi
    Citation: Gut Pathogens 2023 15:10
  6. Parkinson’s disease (PD) is the second most common neurodegenerative disease worldwide. Gut dysbiosis is hypothesized to cause PD; therefore, whether probiotics can be used as adjuvants in the treatment of PD ...

    Authors: Jong Mi Park, Sang Chul Lee, Chorom Ham and Yong Wook Kim
    Citation: Gut Pathogens 2023 15:9
  7. The prophylactic use of antimicrobials and zinc oxide (ZnO) in pig production was prohibited by the European Union in 2022 due to potential associations between antimicrobial and heavy metal usage with antimic...

    Authors: Daniel Ekhlas, Juan M. Ortiz Sanjuán, Edgar G. Manzanilla, Finola C. Leonard, Héctor Argüello and Catherine M. Burgess
    Citation: Gut Pathogens 2023 15:8
  8. Eradication of Helicobacter pylori provides the most effective treatment for gastroduodenal diseases caused by H. pylori infection. Clarithromycin, a member of the macrolide family, still remains the most importa...

    Authors: Bipul Chandra Karmakar, Sangita Paul, Surajit Basak, Manisha Ghosh, Piyali Mukherjee, Rajashree Das, Sujit Chaudhuri, Shanta Dutta and Asish Kumar Mukhopadhyay
    Citation: Gut Pathogens 2023 15:7
  9. CKLF-like MARVEL transmembrane domain containing 3 (CMTM3) plays an important role in cancer development. Although Helicobacter pylori (H. pylori) infection is a main cause of gastric cancer, the function of CMTM...

    Authors: Jing Zhang, Jing Ning, Weiwei Fu, Yanyan Shi, Jing Zhang and Shigang Ding
    Citation: Gut Pathogens 2023 15:6
  10. The emerging pathogen Campylobacter concisus has been isolated from patients with gastrointestinal diseases; however, it is also present in the gut of healthy individuals. The aim of this study was to compare IL-...

    Authors: Marta Emilie Yde Aagaard, Karina Frahm Kirk, Hans Linde Nielsen, Rudi Steffensen and Henrik Nielsen
    Citation: Gut Pathogens 2023 15:5
  11. Coagulase negative staphylococci (CoNS) are a heterogeneous group of bacteria that colonize different types of human epithelia. These bacteria have a highly variable pathogenic potential ranging from avirulent...

    Authors: Robin Louail, Franklin Florin, Sophie Bernard, Jean-Baptiste Michaud, Jonathan Breton, Najate Achamrah, Marie-Pierre Tavolacci, Moïse Coëffier and David Ribet
    Citation: Gut Pathogens 2023 15:4
  12. Paediatric pneumonia is a respiratory infection that affects infants and young children under the age of 3. This disease is the leading cause of infant and child mortality in developing countries because of th...

    Authors: Zhiying Tian, Asif Iqbal Khan, Ata Ur Rehman, Ting Deng, Chao Ma and Liang Wang
    Citation: Gut Pathogens 2023 15:2
  13. Necrotic enteritis (NE) is an infectious intestinal disease caused by Clostridium perfringens (C. perfringens) that is now re-emerging and causing concern within the poultry industry. Previously, the supplementat...

    Authors: Nanshan Qi, Shaobing Liu, Fangquan Yan, Bing Chen, Shilin Wu, Xuhui Lin, Zhuanqiang Yan, Qingfeng Zhou, Shenquan Liao, Juan Li, Minna Lv, Haiming Cai, Junjing Hu, Jianfei Zhang, Youfang Gu and Mingfei Sun
    Citation: Gut Pathogens 2023 15:1
  14. Colorectal cancer (CRC) is the third most diagnosed cancer and the second most common cause of cancer deaths worldwide. CRC patients present with an increase in pathogens in their gut microbiota, such as polyk...

    Authors: Manon Oliero, Roy Hajjar, Thibault Cuisiniere, Gabriela Fragoso, Annie Calvé, François Dagbert, Rasmy Loungnarath, Herawaty Sebajang, Frank Schwenter, Ramses Wassef, Richard Ratelle, Éric De Broux, Carole S. Richard and Manuela M. Santos
    Citation: Gut Pathogens 2022 14:51
  15. Colorectal cancer (CRC) is a multifactorial disease with genetic and environmental factors. Regional differences in risk factors are an important reason for the different incidences of CRC in different regions.

    Authors: Han Shuwen, Wu Yinhang, Zhao Xingming, Zhuang Jing, Liu Jinxin, Wu Wei and Ding Kefeng
    Citation: Gut Pathogens 2022 14:50
  16. Microbial dysbiosis has been closely linked with colorectal cancer development. However, data is limited regarding the relationship of the mucosal microbiome, adenomatous polyps and dietary habits. Understandi...

    Authors: Katherine M. Watson, Kyla N. Siemens, Sudarshan Anand, Ivy H. Gardner, Thomas J. Sharpton, Elizabeth N. Dewey, Robert Martindale, Christopher A. Gaulke and Vassiliki Liana Tsikitis
    Citation: Gut Pathogens 2022 14:49
  17. Previous evidence has shown that the gut microbiota plays a role in the development and progression of colorectal cancer (CRC). This study aimed to provide quantitative analysis and visualization of the intera...

    Authors: Han Chen, Jianhua Jiao, Min Wei, Xingzhou Jiang, Ruoyun Yang, Xin Yu, Guoxin Zhang and Xiaoying Zhou
    Citation: Gut Pathogens 2022 14:48
  18. The effects of proton-pump inhibitors (PPIs) on the infant microbiome remain unclear. Swedish pilot cohort study to assess the longitudinal effect of long-term PPI on the infant gut microbiome, including ten n...

    Authors: Nele Brusselaers, Marcela Pereira, Johan Alm, Lars Engstrand and Helene Engstrand Lilja
    Citation: Gut Pathogens 2022 14:47
  19. Emerging evidence suggests that gut microbiota plays a predominant role in Crohn’s disease (CD). However, the microbiome alterations in the early stage of CD patients still remain unclear. The present study ai...

    Authors: Xianzong Ma, Xiaojuan Lu, Wenyu Zhang, Lang Yang, Dezhi Wang, Junfeng Xu, Yan Jia, Xin Wang, Hui Xie, Shu Li, Mingjie Zhang, Yuqi He, Peng Jin and Jianqiu Sheng
    Citation: Gut Pathogens 2022 14:46
  20. Campylobacter jejuni is a pervasive pathogen of major public health concern with a complex ecology requiring accurate and informative approaches to define pathogen diversity during outbreak investigations. Source...

    Authors: Bilal Djeghout, Samuel J. Bloomfield, Steven Rudder, Ngozi Elumogo, Alison E. Mather, John Wain and Nicol Janecko
    Citation: Gut Pathogens 2022 14:45
  21. Campylobacteriosis represents a global public health threat with various socio-economic impacts. Among different Campylobacter species, Campylobacter jejuni (C. jejuni) is considered to be the foremost Campylobac...

    Authors: Yara El dessouky, Salma W. Elsayed, Nehal Adel Abdelsalam, Nehal A. Saif, Avelino Álvarez-Ordóñez and Mohamed Elhadidy
    Citation: Gut Pathogens 2022 14:44
  22. Helicobacter pylori infection is a well-recognized cause of gastric diseases, including chronic gastritis, peptic ulcer, and gastric cancer. Vacuolating cytotoxin-A (VacA) and cytotoxin-associated gene A protein ...

    Authors: Ichiro Imoto, Satoko Oka, Masaki Katsurahara, Misaki Nakamura, Taro Yasuma, Junko Akada, Corina N. D’Alessandro-Gabazza, Masaaki Toda, Noriyuki Horiki, Esteban C. Gabazza and Yoshio Yamaoka
    Citation: Gut Pathogens 2022 14:43
  23. Vibrio cholerae, the causative agent of cholera, is a well-studied species, whereas Vibrio metoecus is a recently described close relative that is also associated with human infections. The availability of V. met...

    Authors: Fabini D. Orata, Nora A. S. Hussain, Kevin Y. H. Liang, Dalong Hu and Yann F. Boucher
    Citation: Gut Pathogens 2022 14:42
  24. The natural protoberberine jatrorrhizine (JA) is reported to have several medicinal properties and a significant effect on the gut microbiota of mice. The regulation of gut microbiota is generally known to pla...

    Authors: Jia Ling Zhang, Min Na Zhang, Hong Gang Wang, Xiao Zhong Yang and Cheng Gong Yu
    Citation: Gut Pathogens 2022 14:41
  25. Type-1 Diabetes Mellitus (T1DM) is regarded as a multifunctional, immune-related disease which causes massive destruction of islet β-cells in pancreas resulting in hyperglycemic, hypoinsulinemia and hyperlipid...

    Authors: Nimra Zafar Siddiqui, Ata Ur Rehman, Waleed Yousuf, Asif Iqbal khan, Nabeel Ahmed Farooqui, Shizhu Zang, Yi Xin and Liang Wang
    Citation: Gut Pathogens 2022 14:39
  26. We evaluated the microbiota in the stomach of Gastroesophageal Reflux Disease (GERD) patients. We compared Erosive Reflux Disease (ERD) to gastritis and Non-erosive Reflux Disease (NERD) subjects by 16S rRNA a...

    Authors: Titong Sugihartono, Kartika Afrida Fauzia, Muhammad Miftahussurur, Langgeng Agung Waskito, Purwo Sri Rejeki, Reny I’tishom, Ricky Indra Alfaray, Dalla Doohan, Rizki Amalia, Camilia Metadea Aji Savitri, Yudith Annisa Ayu Rezkitha, Junko Akada, Takashi Matsumoto and Yoshio Yamaoka
    Citation: Gut Pathogens 2022 14:38
  27. Intestinal dysbiosis has been reported to be associated with celiac disease (CeD) in Western populations but little is known in other populations who have different dietary lifestyle and genetic background. Th...

    Authors: Mohammad El Mouzan, Abdulrahman Al-Hussaini, Gloria Serena, Asaad Assiri, Ahmed Al Sarkhy, Mohammad Al Mofarreh, Mona Alasmi and Alessio Fasano
    Citation: Gut Pathogens 2022 14:37
  28. Clostridioides difficile infection (CDI) rates and outcomes can vary based on differences in testing strategy. Our aim was to assess the prevalence of toxin detection in inflammatory bowel disease (IBD) when comp...

    Authors: Rachel Bernard, Muhammad B. Hammami, Forest W. Arnold, Brian Mcgrath, Alieysa Patel, Brandon Wuerth, Maribeth R. Nicholson, Krishna Rao and Dejan Micic
    Citation: Gut Pathogens 2022 14:36
  29. Little is known of possible selection and replication of SARS-CoV-2 in the intestines and if viral load in feces is associated with severity of disease. Therefore, sequence variations of the spike region in st...

    Authors: Thomas Beck-Friis, Ambjörn Kärmander, Kristina Nyström, Hao Wang, Magnus Gisslén, Lars-Magnus Andersson and Heléne Norder
    Citation: Gut Pathogens 2022 14:35
  30. Gastrointestinal manifestations of coronavirus disease 2019 (COVID-19) appear to be substantial. Fecal calprotectin is a promising biomarker in COVID-19 associated gastrointestinal inflammation; however, its r...

    Authors: Deasy Natalia Adriana, Titong Sugihartono, Iswan Abbas Nusi, Poernomo Boedi Setiawan, Herry Purbayu, Ummi Maimunah, Ulfa Kholili, Budi Widodo, Husin Thamrin, Amie Vidyani, Hasan Maulahela, Yoshio Yamaoka and Muhammad Miftahussurur
    Citation: Gut Pathogens 2022 14:34
  31. Campylobacter (C.) species are the most common bacterial cause of foodborne diarrhea in humans. Despite colonization, most animals do not show clinical signs, making recognition of affected flocks and disruption...

    Authors: Janina Rzeznitzeck, Gerhard Breves, Ivan Rychlik, Frederic J. Hoerr, Alexandra von Altrock, Alexandra Rath and Silke Rautenschlein
    Citation: Gut Pathogens 2022 14:33
  32. Kenya introduced Rotarix® (GlaxoSmithKline Biologicals, Rixensart, Belgium) vaccination into its national immunization programme beginning July 2014. The impact of this vaccination program on the local epidemiolo...

    Authors: Charles N. Agoti, Martin D. Curran, Nickson Murunga, Moses Ngari, Esther Muthumbi, Arnold W. Lambisia, Simon D. W. Frost, Barbara A. Blacklaws, D. James Nokes and Lydia N. Drumright
    Citation: Gut Pathogens 2022 14:32
  33. The emergence of the novel GII.17 Kawasaki 2014 norovirus variant raising the interest of the public, has replaced GII.4 as the predominant cause of noroviruses outbreaks in East Asia during 2014–2015. Antigen...

    Authors: Yingyin Liao, Liang Xue, Junshan Gao, Yueting Zuo, Yanhui Liang, Yueting Jiang, Weicheng Cai, Jiale Yang, Jumei Zhang, Yu Ding, Moutong Chen, Aiwu Wu, Xiaoxia Kou and Qingping Wu
    Citation: Gut Pathogens 2022 14:31
  34. Obesity is a worldwide health problem and a significant risk factor for diabetes and cardiovascular diseases. Gut microbiota (GM) plays an essential role in obesity, and prebiotics such as polyphenols could be...

    Authors: Mohamed Mokrani, Kamel Charradi, Ferid Limam, Ezzedine Aouani and Maria C. Urdaci
    Citation: Gut Pathogens 2022 14:30
  35. Acute liver failure (ALF) patients are often accompanied by severe energy metabolism abnormalities and intestinal microecological imbalance. The intestinal mucosal barrier is severely damaged. Intestinal endot...

    Authors: Pan Cao, Qian Chen, Chunxia Shi, Luwen Wang and Zuojiong Gong
    Citation: Gut Pathogens 2022 14:29
  36. In India, multi-drug resistance in Salmonella enterica serovar Typhimurium poses a significant health threat. Indeed, S. Typhimurium has remained unknown for a large portion of its genome associated with various ...

    Authors: Nirmal Kumar Mohakud, Rakesh Kumar Panda, Saumya Darshana Patra, Bikash Ranjan Sahu, Mrinmoy Ghosh, Gajraj Singh Kushwaha, Namrata Misra and Mrutyunjay Suar
    Citation: Gut Pathogens 2022 14:28
  37. Neutrophil extracellular traps (NETs) are extracellular reticular fibrillar structures composed of DNA, histones, granulins and cytoplasmic proteins that are delivered externally by neutrophils in response to ...

    Authors: Feng Chen, Yongqiang Liu, Yajing Shi, Jianmin Zhang, Xin Liu, Zhenzhen Liu, Jipeng Lv and Yufang Leng
    Citation: Gut Pathogens 2022 14:27
  38. Inflammatory bowel disease (IBD), a chronic gut immune dysregulation and dysbiosis condition is rapidly increasing in global incidence. Regardless, there is a lack of ideal diagnostic markers, while convention...

    Authors: Xinwei Xu, Dickson Kofi Wiredu Ocansey, Sanhua Hang, Bo Wang, Samuel Amoah, Chengxue Yi, Xu Zhang, Lianqin Liu and Fei Mao
    Citation: Gut Pathogens 2022 14:26
  39. Composition of gut microbiota has recently been suggested as a key factor persuading the pathogenesis of numerous human diseases including hepatic cirrhosis.

    Authors: Zeinab Ashour, Rasha Shahin, Zeinab Ali-Eldin, Mohamed El-Shayeb, Tarek El-Tayeb and Salwa Bakr
    Citation: Gut Pathogens 2022 14:25
  40. Helicobacter pylori eradication by the conventional clarithromycin therapy has largely dropped in the recent years possibly due to antimicrobial resistance. Hence, levofloxacin-based regimen has been used as salv...

    Authors: Eman T. Azab, Abrar K. Thabit, Sean McKee and Aymen Al-Qiraiqiri
    Citation: Gut Pathogens 2022 14:24
  41. Cronobacter sakazakii is a foodborne pathogen that causes septicemia, meningitis, and necrotizing enterocolitis in neonates and infants. The current research details the full genome sequences of two extremely per...

    Authors: Flavia J. Negrete, Katie Ko, Hyein Jang, Maria Hoffmann, Angelika Lehner, Roger Stephan, Séamus Fanning, Ben D. Tall and Gopal R. Gopinath
    Citation: Gut Pathogens 2022 14:23
  42. Clostridioides difficile (C. difficile) is a gram-positive, spore-forming, anaerobic bacterium known to be the most common cause of hospital-acquired and antibiotic-associated diarrhea. C. difficile infection rat...

    Authors: Charlotte Nyblade, Viviana Parreno, Peng Zhou, Casey Hensley, Vanessa Oakes, Hassan M. Mahsoub, Kelsey Kiley, Maggie Frazier, Annie Frazier, Yongrong Zhang, Hanping Feng and Lijuan Yuan
    Citation: Gut Pathogens 2022 14:22
  43. Enterococcus faecium is an emerging ESKAPE bacterium that is capable of causing severe public health complications in humans. There are currently no licensed treatments or vaccinations to combat the deadly pathog...

    Authors: Jyotirmayee Dey, Soumya Ranjan Mahapatra, T. Kiran Raj, Taranjeet Kaur, Parul Jain, Arushi Tiwari, Shubhransu Patro, Namrata Misra and Mrutyunjay Suar
    Citation: Gut Pathogens 2022 14:21
  44. Intestinal microbiota transplantation (IMT) has been recognized as an effective treatment for recurrent Clostridium difficile infection (rCDI) and a novel treatment option for other diseases. However, the safety ...

    Authors: Chong Chen, Liyu Chen, Dayong Sun, Cailan Li, Shiheng Xi, Shihua Ding, Rongrong Luo, Yan Geng and Yang Bai
    Citation: Gut Pathogens 2022 14:20
  45. Over the past decade, the development of next-generation sequencing for human microbiota has led to remarkable discoveries. The characterization of gastric microbiota has enabled the examination of genera asso...

    Authors: Langgeng Agung Waskito, Yudith Annisa Ayu Rezkitha, Ratha-korn Vilaichone, Titong Sugihartono, Syifa Mustika, I Dewa Nyoman Wibawa, Yoshio Yamaoka and Muhammad Miftahussurur
    Citation: Gut Pathogens 2022 14:19
  46. Klebsiella quasipneumoniae is an opportunistic pathogen causing antibiotic-resistant infections of the gastrointestinal tract in many clinical cases. Orally delivered bioactive Klebsiella-specific antimicrobial p...

    Authors: Indre Karaliute, Rima Ramonaite, Jurga Bernatoniene, Vilma Petrikaite, Audrius Misiunas, Erna Denkovskiene, Ausra Razanskiene, Yuri Gleba, Juozas Kupcinskas and Jurgita Skieceviciene
    Citation: Gut Pathogens 2022 14:17