The present study was conducted to investigate the possible association between gut microbes and immunity among healthy middle-aged and elderly individuals in southwest China. A total of 148 healthy adults age...
Authors: Xi Shen, Junjie Miao, Qun Wan, Shuyue Wang, Ming Li, Fangfang Pu, Guoqing Wang, Wei Qian, Qian Yu, Francesco Marotta and Fang He
The commensal, symbiotic, and pathogenic microbial community which resides inside our body and on our skin (the human microbiome) can perturb host energy metabolism and immunity, and thus significantly influen...
Authors: Dachao Liang, Ross Ka-Kit Leung, Wenda Guan and William W. Au
Janibacter melonis and other member of this genus are known to cause bacteremia and serious clinical comorbidities, but there is no study reporting about pathogenicity attributes of J. melonis. Janibacter terrae ...
Lactobacillus pentosus SLC13 is a high exopolysaccharide (EPS)-producing strain with broad-spectrum antimicrobial activity and the ability to grow in simulated gastrointestinal conditions. SLC13 was isolated from...
Authors: Min-Lang Huang, Jing-Yao Huang, Cheng-Yen Kao and Tony J. Fang
Helicobacter pylori (H. pylori) causes a diversity of gastric diseases. Rapid urease tests (RUT) are well established for the point-of-care, invasive diagnosis of H. pylori infection. ...
Authors: Werner Dolak, Ceren Bilgilier, Alexander Stadlmann, Judith Leiner, Andreas Püspök, Wolfgang Plieschnegger, Franz Siebert, Friedrich Wewalka, Rainer Schöfl, Ursula Huber-Schönauer, Christian Datz, Susanne Biowski-Frotz, Christoph Högenauer, Christiane Schrutka-Kölbl, Athanasios Makristathis, Maximilian Schöniger-Hekele…
Of 48 bacteria belonging to the family Enterobacteriaceae tested from urban sludge samples, one Escherichia coli isolate was resistant to colistin and possessed the resistance marker gene mcr-1 found for the firs...
Authors: Aminul Islam, Zillur Rahman, Shirajum Monira, Md. Anisur Rahman, Andrew Camilli, Christine M. George, Niyaz Ahmed and Munirul Alam
The ability of Shigella to invade, colonize, and eventually kill host cells is influenced by many virulence factors. However, there is no analysis of related genes in Jiangsu Province of China so far. Shigella fl...
Authors: Wenting Fan, Huimin Qian, Wenkang Shang, Chen Ying, Xuedi Zhang, Song Cheng, Bing Gu and Ping Ma
Salmonella is recognized as a common bacterial cause of foodborne diarrheal illness worldwide, and animal or its food products have been the most common vehicles of the Salmonella infe...
Authors: Mei Long, Hua Yu, Li Chen, Guoyan Wu, Siyue Zhao, Wenwen Deng, Shujuan Chen, Kang Zhou, Shuliang Liu, Li He, Xiaoling Ao, Yubao Yan, Menggen Ma, Hongning Wang, Margaret A. Davis, Lisa Jones…
After an environmental disaster, the affected community is at increased risk for persistent abdominal pain but mechanisms are unclear. Therefore, our study aimed to determine association between abdominal pain...
Authors: NurFadhilah Yusof, Nurhazwani Hamid, Zheng Feei Ma, Rona Marie Lawenko, Wan Mohd Zahiruddin Wan Mohammad, Deirdre A. Collins, Min Tze Liong, Toshitaka Odamaki, Jinzhong Xiao and Yeong Yeh Lee
The present research was conducted to investigate the influence of a low, single dose of LPS, which does not result in any clinical symptoms of intoxication on the expression of selected neuropeptides within t...
Authors: Anita Mikołajczyk, Sławomir Gonkowski and Dagmara Złotkowska
In the original version of this article [1], published on 17 November 2017, Table 2 contains an error: the first “T” in the first sequence in the column ‘Consensus direct repeats (CDRs) sequences’ has been incorr...
Many Escherichia coli strains are considered to be a component of the normal flora found in the human and animal intestinal tracts. While most E. coli strains are commensal, some strains encode virulence factors ...
Authors: Yan Feng, Anthony Mannion, Carolyn M. Madden, Alton G. Swennes, Catherine Townes, Charles Byrd, Robert P. Marini and James G. Fox
Clostridium difficile is a Gram-positive anaerobe and the leading cause of antibiotic-associated diarrhea worldwide. The emergence of ribotype 027 (RT027) strains is associated with in...
The aim of this study was to generate a reference set of Salmonella enterica genomes isolated from wildlife from the United States and to determine the antimicrobial resistance and virulence gene profile of the i...
Authors: Milton Thomas, Gavin John Fenske, Linto Antony, Sudeep Ghimire, Ronald Welsh, Akhilesh Ramachandran and Joy Scaria
Recent advances in next-generation sequencing technologies have enabled comprehensive analysis of the gut microbiota, which is closely linked to the health of the host. Consequently, several studies have explo...
Authors: Junhyung Kim, Jae-Uk An, Woohyun Kim, Soomin Lee and Seongbeom Cho
Vibrio vulnificus, an opportunistic pathogen, is the causative agent of life-threatening septicemia and severe wound infections. However, the pathogenicity and virulence factors of V. ...
Authors: Junhang Pan, Yi Sun, Wenwu Yao, Haiyan Mao, Yanjun Zhang and Muyuan Zhu
Clostridium perfringens is ubiquitous in nature. It is a normal inhabitant in the intestinal tract of animals and humans. As the primary etiological agent of gas gangrene, necrosis and...
Authors: Charles Li, Xianghe Yan and Hyun S. Lillehoj
Many bacteria and archaea possess a defense system called clustered regularly interspaced short palindromic repeats (CRISPR) associated proteins (CRISPR-Cas system) against invaders such as phages or plasmids....
The waterborne diarrheagenic bacterium Vibrio cholerae, cause of the pandemic cholera disease, thrives in a variety of environments ranging from estuarine waters to the human intestinal tract. This species has tw...
Authors: Andrés Fuentes Flores, Ignacio Sepúlveda Cisternas, José Ignacio Vásquez Solis de Ovando, Alexia Torres and Víctor Antonio García-Angulo
Campylobacter is considered to be the leading cause of human bacterial gastroenteritis, of which poultry is the main reservoir. Campylobacter contaminated chicken products are a major ...
Authors: Tengfei Zhang, Jun Dong, Yiluo Cheng, Qin Lu, Qingping Luo, Guoyuan Wen, Guoping Liu and Huabin Shao
Clostridium difficile infection (CDI) leads to the onset of antibiotic-associated diarrhea (AAD) and a wide range of gastrointestinal pathologies. Currently, CDI is one of the most imp...
Authors: Marina Muñoz, Milena Camargo, Dora Inés Ríos-Chaparro, Paula Gómez, Manuel Alfonso Patarroyo and Juan David Ramírez
Infections with multi-drug resistant (MDR) Gram-negative bacteria including Pseudomonas aeruginosa (PA) have become a serious threat particularly in hospitalized patients with immunopathological co-morbidities. T...
Authors: Anne Grunau, Ulrike Escher, Anja A. Kühl, Stefan Bereswill and Markus M. Heimesaat
Vibrio cholerae is responsible for the cause of severe life-threatening infection known as cholera. The study aimed to analyze the genetic make-up of V. cholerae O139 isolates from India ...
Bilophila wadsworthia is a major member of sulfidogenic bacteria in human gut, it was originally recovered from different clinical specimens of intra-abdominal infections and recently ...
Authors: Zhou Feng, Wenmin Long, Binhan Hao, Ding Ding, Xiaoqing Ma, Liping Zhao and Xiaoyan Pang
Of 19 environmental Escherichia coli (n = 12) and Klebsiella pneumoniae (n = 7) tested for quinolone resistance-related genes qnrA, qnrB, qnrC, qnrS and qepA, four each of E. coli and K. pneumoniae possessed qnrS
Authors: Zillur Rahman, Aminul Islam, Mahamud-ur Rashid, Fatema-Tuz Johura, Shirajum Monira, Haruo Watanabe, Niyaz Ahmed, Andrew Camilli and Munirul Alam
The global incidence of foodborne infections and antibiotic resistance is recently increased and considered of public health concern. Currently, scarcely information is available on foodborne infections and ES...
Authors: Amira A. Moawad, Helmut Hotzel, Omnia Awad, Herbert Tomaso, Heinrich Neubauer, Hafez M. Hafez and Hosny El-Adawy
There are few studies analyzed concurrently the prevalence and genotypes of Helicobacter pylori infection with the ancestor origins from different ethnics, especially with including minority groups. We recruited ...
Authors: Phawinee Subsomwong, Muhammad Miftahussurur, Ratha-korn Vilaichone, Thawee Ratanachu-ek, Rumiko Suzuki, Junko Akada, Tomohisa Uchida, Varocha Mahachai and Yoshio Yamaoka
Enterotoxigenic Escherichia coli (ETEC) cause infectious diarrhea and diarrheal death. However, the genetic properties of pathogenic strains vary spatially and temporally, making prevention and treatment difficul...
Authors: Taesoo Kwon, Si-yun Chung, Young-Hee Jung, Su-Jin Jung, Sang-Gyun Roh, Je-Seop Park, Cheorl-Ho Kim, Won Kim, Young-Seok Bak and Seung-Hak Cho
The aim of this study was to determine the susceptibility of 88 Lactobacillus isolates derived from chickens to antibiotic substances and to detect drug-resistance genes.
Authors: Marta Dec, Renata Urban-Chmiel, Dagmara Stępień-Pyśniak and Andrzej Wernicki
Ulcerative colitis (UC) as a type of inflammatory bowel disease (IBD), presumed to occur as a consequence of increased immune responses to intestinal microbiota in genetically susceptible individuals. Enteroto...
Authors: Samin Zamani, Sonia Hesam Shariati, Mohammad Reza Zali, Hamid Asadzadeh Aghdaei, Akram Sarabi Asiabar, Saied Bokaie, Bizhan Nomanpour, Leonardo Antonio Sechi and Mohammad Mehdi Feizabadi
During the Spanish colonisation of South America, African slaves and Europeans arrived in the continent with their corresponding load of pathogens, including Helicobacter pylori. Colombian strains have been clust...
Authors: Andrés Julián Gutiérrez-Escobar, Esperanza Trujillo, Orlando Acevedo and María Mercedes Bravo
Salmonella Enteritidis causes intestinal and extra-intestinal infections, but rarely cutaneous infections. It has never been reported to cause carbuncle (a collection of interconnected...
Authors: Wadha Alfouzan, Dieter Bulach, Hidemasa Izumiya, Khaled AlBassam, Simin Sheikh, Nasser Alrubai’aan and M. John Albert
The Campylobacter species usually causes infection between humans and livestock interaction via livestock breeding. The studies of the Campylobacter species thus far in all clinical isolates were to show the many...
Authors: Yi-Chih Chang, Ni Tien, Jai-Sing Yang, Chi-Cheng Lu, Fuu-Jen Tsai, Tsurng-Juhn Huang and I-Kuan Wang
Cryptosporidium is a major cause of diarrhea worldwide in both humans and farm animals with no completely effective treatment available at present. In this study, we assessed the inhib...
Authors: Alexandros Ch Stratakos, Filip Sima, Patrick Ward, Mark Linton, Carmel Kelly, Laurette Pinkerton, Lavinia Stef, Ioan Pet, Tiberiu Iancu, Gratiela Pircalabioru and Nicolae Corcionivoschi
Helicobacter pylori susceptibility to clarithromycin and fluoroquinolone can be determined through Etest or molecular assays. We examined the correlation between phenotypic susceptibil...
Authors: Dana Binyamin, Nina Pastukh, Avi On, Maya Paritsky and Avi Peretz
The incidence of gastric cancer in the Northern city, Hanoi is higher than in the Southern city, Ho Chi Minh, Vietnam. We previously reported that Helicobacter pylori vacA m1 genotype might be responsible for the...
Authors: Tran Thanh Binh, Vo Phuoc Tuan, Ho Dang Quy Dung, Pham Huu Tung, Tran Dinh Tri, Ngo Phuong Minh Thuan, Vu Van Khien, Phan Quoc Hoan, Rumiko Suzuki, Tomohisa Uchida, Tran Thi Huyen Trang and Yoshio Yamaoka
Campylobacter concisus and C. ureolyticus have emerged in recent years as being associated with acute and prolonged gastroenteritis and implicated in the development of inflammatory bo...
Authors: Oralak Serichantalergs, Sirigade Ruekit, Prativa Pandey, Sinn Anuras, Carl Mason, Ladaporn Bodhidatta and Brett Swierczewski
Clostridium difficile is the causative agent of C. difficile infection (CDI) that could be manifested by diarrhea, pseudomembranous colitis or life-threatening toxic megacolon. The spr...
Authors: Jiri Dresler, Marcela Krutova, Alena Fucikova, Jana Klimentova, Veronika Hruzova, Miloslava Duracova, Katerina Houdkova, Barbora Salovska, Jana Matejkova, Martin Hubalek, Petr Pajer, Libor Pisa and Otakar Nyc
The gut microbiota plays an essential role in health and disease of humans. Bacteriophages are the most abundant members of the gut virobiota and display great diversity. Phages can translocate through the muc...
Authors: Marzanna Łusiak-Szelachowska, Beata Weber-Dąbrowska, Ewa Jończyk-Matysiak, Renata Wojciechowska and Andrzej Górski
Clostridium difficile is an anaerobic Gram-positive spore-forming gut pathogen that causes antibiotic-associated diarrhea worldwide. A small number of C. difficile strains express the ...
Authors: Zhong Peng, Sidi Liu, Xiujuan Meng, Wan Liang, Zhuofei Xu, Biao Tang, Yuanguo Wang, Juping Duan, Chenchao Fu, Bin Wu, Anhua Wu and Chunhui Li
Dysbiosis is linked to the cause of several human diseases, many of which having an immunity related component. This work investigated whether mice genetically selected for low or high antibody production disp...
Authors: Ana Carolina da Silva Santos, José Ricardo Jensen, Silvio Luis de Oliveira and Josias Rodrigues
Members of the genus Hafnia have been isolated from the feces of mammals, birds, reptiles, and fish, as well as from soil, water, sewage, and foods. Hafnia alvei is an opportunistic pathogen that has been implica...
Authors: Hye Seon Song, Joon Yong Kim, Yeon Bee Kim, Myeong Seon Jeong, Jisu Kang, Jin-Kyu Rhee, Joseph Kwon, Ju Suk Kim, Jong-Soon Choi, Hak-Jong Choi, Young-Do Nam and Seong Woon Roh
The serine protease HtrA is an important factor for regulating stress responses and protein quality control in bacteria. In recent studies, we have demonstrated that the gastric pathogen Helicobacter pylori can s...
Authors: Aileen Harrer, Manja Boehm, Steffen Backert and Nicole Tegtmeyer
Unrelated spore-forming bacteria share unique characteristics stemming from the presence of highly resistant endospores, leading to similar challenges in health and disease. These characteristics are related t...
Klebsiella pneumoniae (K. pneumoniae) is an opportunistic pathogen associated with community-acquired infections and nosocomial infections. From 2010 to 2015, K. pneumoniae testing was...
Authors: Bing Lu, Haijian Zhou, Xin Zhang, Mei Qu, Ying Huang and Quanyi Wang
Campylobacter is a well-known bacterial pathogen for triggering acute gastroenteritis in humans both in developed and developing countries. This organism is highly resistant to fluoroq...
Authors: Piyali Mukherjee, Shanta Dutta and Asish K. Mukhopadhyay
The pH of the human gastric mucosa varies around 2.5 so that only bacteria with strong acidic stress tolerance can colonize it. The ulcer causing Helicobacter pylori thrives in the gastric mucosa. We analyse the ...
Authors: Hilde S. Vollan, Tone Tannæs, Dominique A. Caugant, Gert Vriend and Geir Bukholm
Recent studies show that some Escherichia coli strains possessing a gene cluster named the pks island might have a causative role in the development of human colorectal cancer (CRC). In several reports from Europ...
Mycobacterium avium subspecies paratuberculosis (MAP) is the causative agent of Johne’s disease in ruminants and is associated with Crohn’s disease (CD) in humans, although the latter ...
Authors: Nicole Parrish, Aravinda Vadlamudi and Neil Goldberg
Campylobacter jejuni infections are of rising importance worldwide. Given that innate immune receptors including nucleotide-oligomerization-domain-2 (Nod2) are essentially involved in ...
Authors: Stefan Bereswill, Ursula Grundmann, Marie E. Alutis, André Fischer, Anja A. Kühl and Markus M. Heimesaat
